No one should think that I mean to explain the entire subject matter of this great book of the prophet Isaiah in one brief sermon, since it contains all the mysteries of the lord. It prophesies that Emmanuel is to be born of a virgin and accomplish marvelous works and signs. It predicts his death, burial and resurrection from the dead as the Savior of all men. Whatever is proper to holy Scripture, whatever can be expressed in human language and understood by the human mind, is contained in the book of Isaiah.
-- Saint Jerome from a commentary on Isaiah
